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The 22 percent reduction in major cardiac events (relative to placebo) associated with a 6 percent increase in HDL cholesterol is consistent with an analysis of the results of the Helsinki Heart Study, a primary-prevention trial with gemfibrozil, which suggested that an 8 percent increase in HDL cholesterol would be expected to result in a 23 percent reduction in such events.
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Fenofibrate is used with a low-fat diet, exercise, and sometimes with other medications to reduce the amounts of fatty substances such as cholesterol and triglycerides in the blood and to increase the amount of HDL (high-density lipoprotein; a type of fatty substance that decreases the risk of heart disease) in the blood.
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Los hallazgos pueden ayudar tambin a explicar por qu las personas que hacen ejercicio no tienen tantos problemas cognitivos a medida que envejecen: El ejercicio ayuda a estabilizar los niveles de glucosa en sangre.
There is evidence for significant LDL cholesterol lowering from even extremely low, less than daily, statin doses ().
Halpern concurri en que los hallazgos tendrn implicaciones amplias en la comprensin de los mecanismos subyacentes en que se basan los efectos de ciertas sustancias.
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